Steve Bird • May 6, 2026
The Perfect Memphis To New Orleans Road Trip Itinerary

A Memphis to New Orleans road trip takes you between two of the world’s most iconic music cities.


A 395-mile Memphis to New Orleans road trip takes you from Tennessee, through Mississippi, to Louisiana. You’ll travel from “The Home Of The Blues”, Memphis, Tennessee, past countless historic towns and cities, stunning natural landmarks, incredible feats of engineering, and a diverse array of unique wildlife, to “The Birthplace Of Jazz”, New Orleans, Louisiana.


Read on for your guide to planning a perfect Memphis to New Orleans road trip itinerary.


A Perfect Memphis To New Orleans Road Trip Itinerary: How Far Is It, How Long Will It Take & What Is The Best Route?

The perfect Memphis to New Orleans road trip covers 395 miles (636 kilometres), takes 5 hours 45 minutes to drive, and follows an extremely straightforward route. You head south on I-55 from Memphis, Tennessee, and follow it to its conclusion in LaPlace, Louisiana. You then take I-10 east the rest of the way to your destination in New Orleans, Louisiana.


Best Time For A Memphis to New Orleans Road Trip

The best time to drive a Memphis to New Orleans road trip is between early February and the start of June. This window avoids hurricane season, which hits the Gulf of Mexico between June and October, and is when the region experiences nice warm weather that is not too hot. This is while ensuring you avoid the huge crowds that develop in New Orleans and along the rest of the route during the summer.


It also gives you the chance to be in New Orleans during one of its most legendary events, Mardi Gras, which takes place in either late February or early March every year.



For those who don’t want to travel at this time, late October is another great time to drive to New Orleans. This is because it has similar weather conditions to our original suggestion, and New Orleans is known as one of the best places to spend Halloween in the United States, especially if you are interested in ghost tours.

New Orleans Superdome

Best Place To Stop On A Memphis to New Orleans Road Trip Itinerary

At just under 6 hours, many people will drive a Memphis to New Orleans road trip in one go. However, for those wanting to take their time and soak in everything that the route has to offer, one place is better for an extended stop than any other: Jackson, Mississippi.


Jackson, Mississippi

Jackson, the capital and largest city of Mississippi, is rich in history, culture, and Southern hospitality. Located in the centre of the Mississippi Delta, the city was pivotal during the Civil Rights Movement, featuring key locations such as the Mississippi Civil Rights Museum and the Medgar Evers Home National Monument. These sites offer visitors essential educational experiences highlighting Jackson's significant role in American history.


Moreover, Jackson boasts a lively arts and music scene. The Mississippi Museum of Art showcases rotating exhibitions and a peaceful sculpture garden. The Mississippi Museum of Natural Science provides a glimpse at the local wildlife through its scenic walking paths. The vibrant sounds of live blues, gospel, and jazz fill the streets, reflecting Jackson's rich musical tradition and energetic artistic community; perfect for a Memphis to New Orleans road trip.


The Mississippi State Capitol is an extraordinary Beaux-Arts structure showcasing the state’s political heritage and architecture. Finished in 1903, the building boasts a magnificent dome, marble-clad interiors, and carefully maintained elements such as stained glass, chandeliers, and elaborate columns, all surrounded by well-kept grounds. You can take guided tours of the legislative chambers, gain insights into Mississippi’s governmental operations, and explore exhibits on the state’s history.


Food lovers will enjoy Jackson's classic Southern cuisine, including delicious barbecue and fried catfish, as well as modern farm-to-table meals. The city's friendly atmosphere, historic districts, lush parks, and vibrant festivals make it an attractive place for those interested in authentic Southern culture and heritage.


Best Hotel To Stay At In Jackson, Mississippi – The Westin Jackson

The Westin Jackson is a luxurious, pet-friendly, 4-star hotel situated in downtown Jackson, Mississippi. This establishment seamlessly combines traditional Southern hospitality with modern design. It is well-suited for guests seeking comfort and ease, being conveniently located within walking distance of major cultural sites, including the Mississippi Museum of Art, Thalia Mara Hall, and the Jackson Convention Complex.


Guest rooms are tastefully furnished and feature amenities such as blackout curtains, high-quality bedding, bathrobes, and advanced technologies like a 50-inch LED TV, iPod dock, Wi-Fi, and air conditioning, as well as a fully equipped private bathroom.



The hotel also offers a variety of amenities to enrich your stay, such as the Estelle Wine Bar & Bistro, which serves contemporary Southern-inspired cuisine; the serene Soul Spa for relaxation; a fully equipped 24-hour fitness centre; and an indoor pool for guests to unwind after a day of sightseeing.

Mississippi Capitol, Jackson

Best Things To See On A Memphis To New Orleans Road Trip Itinerary

Southaven, Mississippi

Southaven is a vibrant suburb located directly south of Memphis, just across the state line in Mississippi. It serves as a convenient and comfortable hub for those visiting the area. The city is recognised for its diverse shopping and entertainment options, including the Tanger Outlets Southaven, where guests can shop among a variety of well-known brand outlets.


Its dining options include everything from Cracker Barrel to independent restaurants serving traditional, homemade southern fare. For those interested in live music and events, the BankPlus Amphitheater at Snowden Grove draws major artists thanks to its relaxed outdoor atmosphere, particularly during the warmer seasons.


In addition to shopping and entertainment, Southaven provides easy access to parks and family-oriented attractions. Snowden Grove Park is a favoured recreational area featuring walking paths, sports fields, and spacious picnic areas, while iconic Memphis sites like Graceland are just a short drive away. With its blend of convenience, modern facilities, and proximity to one of the nation’s most celebrated music cities, Southaven is a practical and enjoyable first stop for travellers setting out on a Memphis to New Orleans road trip.


Tunica, Mississippi

Tunica is an energetic city in Northwest Mississippi, celebrated for its casinos, vibrant history, and Southern hospitality, making it an appealing destination for tourists seeking entertainment and adventure. The city’s casinos are among the finest in Mississippi and the broader Southern United States, featuring a variety of options from slot machines and poker tables to live performances and dining establishments, with the Horseshoe Tunica standing out as a key venue for poker enthusiasts.


Tunica also invites visitors to delve into its local history at the Tunica Museum. Here, insights into the area’s past can be discovered, including its African American heritage and the Mississippi River’s significance. Nature enthusiasts can take advantage of nearby attractions like the Tunica RiverPark, which offers picturesque views of the Mississippi River, scenic walking trails, and informative exhibits about the river's history.


With its yearly events, such as music festivals and cultural gatherings, Tunica provides a diverse array of activities to suit all interests.


Vicksburg, Mississippi

Vicksburg is a historically significant river city on the bluffs overlooking the Mississippi River, known for its crucial involvement in the American Civil War. A key highlight of the city is the Vicksburg National Military Park, where visitors can wander through extensive preserved battlefields and view monuments and the restored USS Cairo, an ironclad gunboat. It provides profound insight into the 1863 siege, which was instrumental in shaping the country’s foundation.


The city's elevated position affords beautiful views of the river, and its compact downtown area allows for a seamless blend of historical exploration and leisurely sightseeing. A walk through the historic downtown reveals its rich southern culture, museums, art galleries, stunning architecture, and unique local shops, as well as iconic sites like the Old Courthouse Museum, which offers a richer understanding of the area's history.

Vicksburg Bridge

Hammond, Louisiana

Hammond, a friendly small city in southeast Louisiana, is often referred to as the "Strawberry Capital of America." It honours its agricultural heritage through the vibrant Ponchatoula Strawberry Festival each spring, attracting visitors with delicious food, lively music, and a warm community atmosphere. The historic downtown is adorned with picturesque streets and filled with boutiques, cafés, and galleries, making it ideal for a stroll or a quick meal.


Additionally, Hammond is home to Southeastern Louisiana University. This infuses the city with youthful vitality and hosts cultural events throughout the year. For outdoor enthusiasts, the region's wetlands and waterways offer ample exploration. With its combination of small-town charm, local character, and proximity to Louisiana's stunning natural scenery, Hammond is a delightful and relaxed stop on a drive across the state.


Manchac Swamp Bridge

The Manchac Swamp Bridge is among the longest bridges in the United States, extending over 20 miles through the hauntingly beautiful wetlands of southern Louisiana. For visitors on a Memphis to New Orleans road trip, it serves not merely as a stop but as an unforgettable journey, seamlessly traversing above cypress trees, bayous, and mist-laden marshes that evoke cinematic imagery.


The raised roadway delivers expansive views of the Manchac Swamp, where one may observe wildlife such as birds and alligators, particularly in the early morning or late afternoon. This stretch of highway offers a uniquely atmospheric experience, presenting travellers with a striking entry into Louisiana’s swamp landscapes as they near New Orleans.


Maurepas Swamp Wildlife Management Area

Located in southeastern Louisiana between Baton Rouge and New Orleans, the Maurepas Swamp Wildlife Management Area offers visitors a chance to discover one of the state's prominent ecosystems. This vast cypress-tupelo swamp features trees adorned with moss, winding bayous, and a variety of wildlife, including alligators, turtles, deer, and many bird species. The area provides a peaceful escape where people can appreciate the pristine beauty of Louisiana's wetlands.



Outdoor enthusiasts can enjoy activities such as fishing, kayaking, and wildlife watching throughout the swamp, with waterways that delve deep into this serene environment. Certain designated areas allow for seasonal hunting, while nature lovers can relish the tranquil setting and beautiful scenery. Maurepas Swamp Wildlife Management Area presents an excellent opportunity for travellers seeking an authentic outdoor adventure in Louisiana and a deeper understanding of the region’s rich natural heritage.

Maurepas Swamp

Lake Pontchartrain

Situated just north of New Orleans, Lake Pontchartrain encompasses 631 square miles, ranking it as the 10th largest natural lake in the United States and the fourth largest within a single state. It is especially famous for the Lake Pontchartrain Causeway, a marvel of engineering that stretches 23.88 miles across the centre of the lake and is acknowledged as the longest continuous bridge over water in the world.


Whether you decide to traverse the causeway to take in its breathtaking views, which are rarely seen elsewhere, or prefer to relax by the lakeshore while observing the local wildlife and appreciating the tranquil scenery before venturing into the city, Lake Pontchartrain serves as an ideal concluding destination for any road trip from Memphis to New Orleans, Louisiana.


Final Thoughts On The Perfect Memphis To New Orleans Road Trip Itinerary

A Memphis to New Orleans road trip is an incredible expedition between two cities with vast musical heritages that lets you experience many of the nation’s cultures and its’ rich history. This guide contains everything you need to plan your perfect road trip itinerary, including when to go, the route to take, what to see, and where to stay along the way.


All you have left to do now is decide what to take with you and start budgeting and booking everything, so you can look forward to enjoying the perfect road trip for yourself as soon as possible. We also have a helpful guide on the best areas to stay in New Orleans, Louisiana, which you’ll find here.



Anyone interested in continuing the drive may also enjoy our selection of guides on road trips from New Orleans, Louisiana. These include:

A road trip from New Orleans to Miami

A road trip from New Orleans to Los Angeles

A road trip from New Orleans to Boston

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